pentobarbital will minimize the extent or impact of aripiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lessen the level or influence of diltiazem by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
With therapeutic doses of TCAs, barbiturates raise metabolism and reduce blood concentrations of TCAs.
This drug may perhaps raise the metabolism of estradiol when administered concurrently; people on oral contraceptives are becoming Expecting when concurrently taken care of with antiepileptic drugs; suggest an alternate contraceptive approach to Gals having this drug
pentobarbital will lessen the extent or impact of nicardipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will reduce the extent or outcome of bosentan by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unknown.
Monoamine oxidase inhibitors (MAOI) might inhibit barbiturate metabolism and prolong barbiturate effects; keep track of closely
Reserve concomitant prescribing of such drugs in patients for whom other cure choices are insufficient. Limit dosages and durations on the minimum required. Observe intently for indications of respiratory depression and sedation.
pentobarbital will lower the level or effect of conjugated estrogens, vaginal by impacting check here hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will reduce the level or influence of doravirine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or influence of tinidazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
buprenorphine subdermal implant and pentobarbital each boost sedation. Prevent or Use Alternate Drug. Restrict use to clients for whom choice procedure options are inadequate
Physical exercise caution when administered to patients with acute or Persistent ache; could lead to paradoxical pleasure or significant indications can be masked
Withdrawal signs or symptoms come about in infants born to moms who receive barbiturates through the entire final trimester of pregnancy